I'm in the same boat you're in. (4 mil Cub, 39 mm keihns, egn needles) I got my mains and dumps drilled out to 1/8'' drill bit (supposed to measure 0.125 '', but I mic'd it at 0.122'') and power jets all the way out most of the time. I'll lean them out a little if I'm competing and not just playing around. Let me know how the 2nd power jet works out for you, Im thinking about doing the same for the colder weather, just to be safe.. BTW, you runnin' a fuel pump? Will a second pj drain the bowls quicker if not?
As far as gearing, Im running 15/42, 1-5 override and I'm through all of the gears as quick as I can shift them.