Couldn't agree with you guys more.
I like to stick to 165 to 185 Cranking compression and add timing, it's easier on the bottom end and...it's easier to adjust timing than it is compression.
As said, that much compression is killing overrev and top end. Shoot for 180ish. With your setup, probably a 20cc domes is what I would shoot for.
Are you flat dragging, hill shooting, duning, etc?